INTRODUCING YOU TO SKINRIGHT INGREDIENTS
Skinright Wrinkle Reduction Gel
The main ingredients:-
Argireline (also known as acetyl hexapeptide 3) is the primary amino acid responsible for the wrinkle reduction of Gel. The sole difference between other anti-wrinkle formulas is that the majority contains 10% Argireline (acetyl hexapeptide 3) , Skinright contains 20% Argireline (acetyl hexapeptide 3) making the latter twice as powerful.
Skinright Gel also contains:-
Hyaluronic Acid to help reduce wrinkles. Each wrinkle treatment uses our unique Liposome Delivery System to further increase wrinkle reduction.
Before you can understand how wrinkle reduction with Skinright Gel works, you need to be familiar with how muscle contractions are stimulated. Remember, it is the attenuation or muting of muscle contraction in the facial muscle groups which allows wrinkles to 'flatten out' and become much less visible. The following is for educational purposes only.
When a nerve fires an 'action potential', which is a wave of cell wall depolarization, it travels down the nerve fibre until it reaches the synaptic cleft which is the gap between the nerve and muscle tissue. The two tissues are not physically connected otherwise all 'flashes' of nerve activity would cause muscle contraction irrespective of the intensity or duration of nerve impulse.
An action potential must reach a certain level before it causes the 'synaptic vesicles' to fuse with the neurone cell wall (called exocytosis). This is rather like a soap bubble bursting and releasing it's contents into the surface that bumps into. In this case however, the contents of the vesicle is a neuro-transmitter called Acetylcholine (Ach). The ACh is therefore released into the synapic cleft space where the majority is taken back up by the nerve or broken down by an enzyme present in the synaptic cleft called Acetylcholisterase. Again if only a small amount of ACh reaches the muscle receptors, a contraction will not take place - so the small amount not re-absorbed or not broken down and reaching the muscle receptors will not cause a muscle contraction.
As the nerve action potential gets more and more intense, more ACh is released eventually leading to sufficient ACh landing on the muscle receptors, which then react by changing shape and letting in sodium ions. The inflood of positively charged Sodium ions sets up a new wave of depolarisation in the muscle fibre causing a contraction.
Note how two vesicles are releasing Achinto the synapsein normal circumstances but now with Anti-Wrinkle Cream applied , only one vesicle fuses with the nerve fibre cell wall, thereby reducing the amount of Ach released or another way of looking at it - increasing the amount of stimulation required before muscle contractions occurs.
Advanced Explanation:
Skinright Gel contains a small hexapeptide that is designed to partially interfere with the SNARE (which is a ternary complex formed by the proteins VAMP, Syntaxin and SNAP-25) This complex intervenes in the process of docking, fusing and exocytosis of these neuro-transmitter vesicles.
Skinright Gel is a mimic of the N-Terminal end of SNAP-25 which can therefore compete for a position in the SNARE complex; thereby modulating it's formation. If the complex is slightly destabilised, the vesicle is not able to release as much neuro-transmitter, thereby muting muscle contraction and helping to prevent the formation & visibility of wrinkles.
Importantly and unlike Botox (Botulinum Toxin A) Skinright Gel does not paralyse completely but acts in a very similar way. Both Botox and Skinright Gel only acts at the site of application.
Skinright Gel
DIRECTIONS
USE ONCE DAILY. IN MORNING AFTER CLEANSING BUT BEFORE ANYTHING ELSE.
INGREDIENTS
LIPOSOMES - are minute spherical capsules comprised of specific lipids, which mimic part of the skins natural structure. Liposome’s are able to entrap a number of materials, which they then protect. Because of their compatibility with the skins natural lipids the liposome’s are able to penetrate deeper into the skin.
ARGIRELINE - ARGIRELINE® is a patented peptide which reduces the depth of wrinkles on the face caused by repeated facial movements, especially in the forehead and around the eyes.
HYALLURONIC ACID - Is a high-molecular naturally occurring material which forms a flexible film on the skin which has the ability to hold large quantities of water helping to effectively moisturise the skin, to help prevent cross-linking.
PML - Minute, multi-layered spheres which entrap active materials, protecting them until they are needed.
The PMLs help to transport the actives through the skin's surface to the lower layers of the skin, where the actives are then slowly released to implant the maximum benefit over a period of time.
Skinright6 Gel - CLINICALLY PROVEN TO REDUCE THE DEPTH OF WRINKLES BY UP TO 50% IN 30 DAYS.
How does it work?
Skinright Gel works by relaxing the muscles in the face that otherwise are engaged in making expressions. These expressions crease the skin and cause lines and wrinkles. The permanent muscle tone present in many facial muscles make the creases look like deep furrows.
Skinright Gel DOES NOT PARALYSE the muscle, it has a gentle effect on the SNARE receptor causing a relaxing effect on muscles not total paralyse. Used on a regular basis Skinright can therefore assist in eliminating the formation of wrinkles and soften and smooth out existing wrinkles.
Skinright is a colourless fragrant -free gel and should be used once daily as a treatment prior to using regular skin care products. Skinright incorporates only pharmaceutical grade raw ingredients to ensure best possible results.
Skinright Gel - for less wrinkled & younger skin - as a maintenance or alternative to muscle paralysing injections
Only Skinright Gel contains a unique blend of super-concentrated Argireline (patented) together with Sodium Hyaluronate that causes wrinkles to melt away while hydrating and moisturising the skin. Skinright is formulated with a pharmaceutical grade "Liposome Delivery System" to maximise delivery of the active ingredient into the target area giving better results ....faster.
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